Platelet yield and recovery following the PRGF-U1 protocol in a Peruvian population.
AbstractObjective: To determine the platelet recovery and yield of the PRGF-U1 protocol in a Peruvian population. Methods: An observational, descriptive and cross-sectional study was conducted with a simple random probability sample of 32 patients who attended the Laboratorio Scalab in Trujillo, Peru. A blood sample was taken from each patient in order to obtain the concentration of platelets and before and after the PRGF-U1 protocol, in order to determine platelet recovery and yield. To compare basal platelet concentrations and platelet recovery and yield with gender and age, the chi-square test, Student's t-distribution and Pearson's correlation coefficient were used considering a significance level of p<0.05. Results: Platelet yield was less than 2.2 in two patients and greater than or equal to 2.2 in 30 patients; platelet recovery was equal to 0.4 in 30 patients and greater than 0.4 in two patients. A statistically significant relationship (p<0.05) between basal platelet count and age was found when comparing basal platelet count, platelet recovery and platelet yield according to gender and age, but no significant relationship between the other variables (p>0.05). Conclusion: The PRGF-U1 protocol presents optimal platelet yield and minimal expected platelet recovery.
2. Dhurat R, Sukesh M. Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective. J Cutan Aesthet Surg. 2014;7(4):189–97.
3. Dhurat R, Sukesh M. Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective. J Cutan Aesthet Surg. 2014;7(4):189–97.
4. Raeissadat SA, Babaee M, Rayegani SM, Hashemi Z, Hamidieh AA, Mojgani P, Fouladi Vanda H. An overview of platelet products (PRP, PRGF, PRF, etc.) in the Iranian studies. Future Sci OA. 2017;3(4):FSO231.
5. Agrawal AA. Evolution, current status and advances in application of platelet concentrate in periodontics and implantology. World J Clin Cases. 2017;5(5):159–71.
6. Samra DJ, Orchard JW. Patterns of platelet-rich plasma use among Australasian sports physicians. BMJ Open Sport Exerc Med. 2015;1(1):e000054.
7. Forni F, Marzagalli M, Tesei P, Grassi A. Platelet gel: applications in dental regenerative surgery. Blood Transfus. 2013;11(1):102–7.
8. Moreno R, Gaspar Carreño M, Jiménez Torres J, Alonso Herreros JM, Villimar A, López Sánchez P. [Methods to obtain platelet-rich plasma and osteoinductive therapeutic use] Farm Hosp. 2015;39(3):130–6.
9. Biino G, Santimone I, Minelli C, Sorice R, Frongia B, Traglia M, Ulivi S, Di Castelnuovo A, Gögele M, Nutile T, Francavilla M, Sala C, Pirastu N, Cerletti C, Iacoviello L, Gasparini P, Toniolo D, Ciullo M, Pramstaller P, Pirastu M, de Gaetano G, Balduini CL. Age- and sex-related variations in platelet count in Italy: a proposal of reference ranges based on 40987 subjects' data. PLoS One. 2013;8(1):e54289.
10. Troussard X, Vol S, Bardet V, Couaillac JP, Fossat C, Luce JC, Maldonado E, Siguret V, Tichet J, Lantieri O, Luce JC, Maldonado E, Siguret V, Tichet J, Lantieri O, Corberand J, French-Speaking Cellular Hematology Group (Groupe Francophone d'Hématologie Cellulaire, GFHC). Full blood count normal reference values for adults in France. J Clin Pathol. 2014;67(4):341–4.
11. Jones CI. Platelet function and ageing. Mamm Genome. 2016;27(7-8):358–66.
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