Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis.

  • Heber Arbildo Escuela de Odontología, Universidad Particular de Chiclayo. Chiclayo. Escuela de Estomatología, Universidad Señor de Sipán. Chiclayo. Centro de Salud Odontológico San Mateo. Trujillo.
  • Luis Gamarra Escuela de Estomatología, Universidad Privada Antonio Guillermo Urrelu. Cajamarca. Facultad de Estomatología, Universidad Nacional de Trujillo. Trujillo.
  • Sandra Rojas Facultad de Estomatología, Universidad Nacional de Trujillo. Trujillo.
  • Edward Infantes Escuela de Estomatología, Universidad Señor de Sipán. Chiclayo. Escuela de Estomatología, Universidad Privada Antonio Guillermo Urrelu. Cajamarca. Escuela de Estomatología, Universidad César Vallejo. Piura.
  • Cesar Lamas Escuela de Odontología, Universidad Católica los Ángeles de Chimbote. Chimbote.
  • Hernán Vásquez Facultad de Odontología, Universidad San Martín de Porres. Lima.

Abstract

Background: There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs). One of the current options is the use of platelet-rich fibrin (PRF). Objective: To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis. Materials and Methods: A literature search was conducted up to February 2017 in the following biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials. The selection criteria included: randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession), with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference. Results: The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration. Conclusion: The literature suggests that the use of PRF in the treatment of PIDs has a beneficial clinical effect when compared to control treatments.

Author Biography

Heber Arbildo, Escuela de Odontología, Universidad Particular de Chiclayo. Chiclayo. Escuela de Estomatología, Universidad Señor de Sipán. Chiclayo. Centro de Salud Odontológico San Mateo. Trujillo.
Editor de Journal of Oral Research.Asesor en Metodología de la Investigación.

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Published
2017-05-24
How to Cite
ARBILDO, Heber et al. Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis.. Journal of Oral Research, [S.l.], v. 6, n. 5, p. 127-135, may 2017. ISSN 0719-2479. Available at: <http://www.joralres.com/index.php/JOR/article/view/joralres.2017.036>. Date accessed: 14 july 2020. doi: https://doi.org/10.17126/joralres.2017.036.
Section
Reviews

Keywords

Platelet-rich fibrin; Periodontitis; Review; Meta-analysis.

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