Comparative performance of the protocol of plasma rich in growth factors - universal 1 (PRGF-U1) for obtaining platelet rich plasma.

  • Augusto Aguirre Facultad de Estomatología, Universidad Nacional de Trujillo.
  • Heber Arbildo Facultad de Estomatología, Universidad Nacional de Trujillo.
  • Javier Peralta Facultad de Estomatología, Universidad Nacional de Trujillo.


Objective: To compare the platelet concentration obtained after application of the protocol of plasma rich in growth factors - universal 1 (PRGF-U1) and the protocol of Anitua and Andia (PRP-A) for obtaining platelet rich plasma. Material and Method: A descriptive, cross-sectional and comparative study was carried out with a simple random probabilistic sample consisting of 16 patients who attended the Periodontics service of the Unit of Second Specialization in Stomatology of the National University of Trujillo. Five blood samples were obtained from each patient, after applying a health questionnaire to rule out any disease or drug consumption, in order to obtain the baseline platelet concentration and that obtained after PRGF-U1 and PRP-A. To compare the platelet concentrations of the two protocols, Student's t-test was used considering a significance level of p <0.05. Results: The baseline platelet concentration was 371,250 ± 68,203 platelets/μL, for PRGF-U1 it was 747,875 ± 121,645 platelets/μL and for PRP-A it was 595,000 ± 129,202 platelets/μL. A statistically significant difference (p<0.001) was found between both protocols. Conclusion: The PRGF-U1 protocol yielded a higher platelet concentration compared to the Anitúa and Andía protocol.


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How to Cite
AGUIRRE, Augusto; ARBILDO, Heber; PERALTA, Javier. Comparative performance of the protocol of plasma rich in growth factors - universal 1 (PRGF-U1) for obtaining platelet rich plasma.. Journal of Oral Research, [S.l.], v. 6, n. 1, p. 16-18, jan. 2017. ISSN 0719-2479. Available at: <>. Date accessed: 22 june 2021. doi:


Platelet rich plasma; Platelet-derived growth factors; Platelet count; Regenerative medicine.