How far are we from periodontal regeneration?

  • Patricio Smith Faculty of Medicine, Pontificia Universidad Católica de Chile


1. Caton J, Nyman S, Zander H. Histometric evaluation of periodontal surgery. II. Connective tissue attachment levels after four regenerative procedures. J Clin Periodontol 1980; 7: 224-231.
2. Bowers GM, Chadroff B, Carnevale R, Mellonig J, Corio R, Emerson J, Stevens M, Romberg E. Histologic evaluation of new attachment apparatus formation in humans. Part I. J Periodontol 1989: 60: 664–674.
3. Nyman S, Gottlow J, Karring T, Lindhe J. The regenerative potential of the periodontal ligament. An experimental study in the monkey. J Clin Periodontol 1982: 9: 257–265.
4. Susin C, Wikesjö U. Regenerative periodontal therapy: 30 years of lessons learned and unlearned. Periodontology 2000 2013: 62: 232–242.
5. Sculean A, Nikolidakis D, Nikou G, Ivanovic A, Chapple IL, Stavropoulos A. Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review. Periodontol 2000. 2015; 68:182-216.
6. Smith PC, Martínez C, Cáceres M, Martínez J. Research on growth factors in periodontology. Periodontology 2000 2015; 67: 234-250.
7. Martínez C, Smith PC, Rodriguez JP. Palma P. Sonic Hedgehog stimulates Proliferation of Human Ligament Periodontal Stem Cells. J Dent Res 2011; 90: 483-488.
8. Bartold PM, Gronthos S, Ivanovski S, Fisher A, Hutmacher DW. Tissue engineered periodontal products. J Periodontal Res. Epub ahead of print.
9. Smith PC, Cáceres M, Martínez C, Oyarzún A, Martínez J. Gingival Wound Healing: An Essential Response Disturbed by Aging? J Dent Res 2015b; 94: 395-402.
How to Cite
SMITH, Patricio. How far are we from periodontal regeneration?. Journal of Oral Research, [S.l.], v. 4, n. 2, p. 82-83, apr. 2015. ISSN 0719-2479. Available at: <>. Date accessed: 04 aug. 2020. doi: