Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy

  • Othoniel Aragon-Martinez Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico. http://orcid.org/0000-0003-2298-404X
  • Karen Loredo-Escobar Periodontics Postgraduate Program, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • Juan Cepeda-Bravo Periodontics Postgraduate Program, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.| Periodontics Clinic, Dentistry School, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • Flavio Martinez-Morales Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • Maria Gonzalez-Rivera Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • Saray Aranda Romo Department of Pharmacology, School of Medicine, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico. http://orcid.org/0000-0002-0379-9626

Abstract

Objective: To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women. Material and methods: For this observational study, medical records, dental examinations, and analyses of saliva samples were carried out in pregnant and nonpregnant women. A p-value of p<0.05 was considered significant. Results: The pregnant women (N = 17) exhibited a lower antioxidant capacity (p-value = 0.0041), higher levels of polyphenols, gingival index, bleeding on probing, and subjects consuming mineral-enriched products (p values from p<0.0001 to 0.0466), and unchanged levels of phosphotungstic acid reactive substances, proteins, oral hygienic habits, plaque index and probing depth (p-values from 0.0683 to 0.8358), in comparison with the nonpregnant women (n = 19). Also, a positive correlation between the gingival index and salivary polyphenol content was observed (r-value = 0.4087, p-value = 0.0202). Conclusion: The salivary polyphenols correlate with plaque-induced gingivitis exacerbated by pregnancy, suggesting a deficiency of salivary antioxidant protection.

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Published
2022-11-03
How to Cite
ARAGON-MARTINEZ, Othoniel et al. Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy. Journal of Oral Research, [S.l.], p. 1-2, nov. 2022. ISSN 0719-2479. Available at: <https://www.joralres.com/index.php/JOralRes/article/view/joralres.2022.032>. Date accessed: 28 nov. 2022. doi: https://doi.org/10.17126/joralres.2022.032.
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Articles