Association between periodontal disease and polycystic ovary syndrome: A scoping review.
Abstract
Background: Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorders in women. It is believed that sex hormones play a role in the maintenance of bone mass and directly or indirectly influence several cell types, including periodontal cells. Objective: To evaluate the association between periodontal disease and PCOS according to the evidence reported in the last decade. Material and Method: A search was made in the biomedical databases: Pubmed, Embase, Scopus, SciELO, Science Direct and SIGLE for the 2007-2017 period. Selection criteria: prospective and retrospective studies reporting the relationship between periodontal disease and PCOS. The methodological quality of the studies was analyzed using the Critical Appraisal Skills Program scale. Results: 10 articles were found: 1 clinical trial and 9 case-control studies. The number of patients ranged from 48 to 196, mean age between 23.3 and 28.1 years, age range between 15 and 45 years. Studies were conducted in Turkey, India and Iran. All the studies presented good methodological quality and a positive association between PCOS and periodontal disease. Conclusion: PCOS shows a positive and significant association with the clinical and molecular parameters of periodontal diseases.References
1. Winnykamien I, Dalibón A, Knoblovits P. Síndrome de ovario poliquístico. Rev Hosp Ital B Aires. 2017;37(1):10–20.
2. Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO. Polycystic ovary syndrome. Rev Dis Primers. 2016;2:16057.
3. Delitala AP, Capobianco G, Delitala G, Cherchi PL, Dessole S. Polycystic ovary syndrome, adipose tissue and metabolic syndrome. Arch Gynecol Obstet. 2017;296(3):405–19.
4. Trikudanathan S. Polycystic ovarian syndrome. Med Clin North Am. 2015;99(1):221–35.
5. Rutkowska AZ, Diamanti-Kandarakis E. Polycystic ovary syndrome and environmental toxins. Fertil Steril. 2016;106(4):948–58.
6. Akcalı A, Bostanci N, Özçaka O, Gümüş P, Öztürk-Ceyhan B, Tervahartiala T, Husu H, Buduneli N, Sorsa T, Belibasakis GN. Gingival Inflammation and Salivary or Serum Granulocyte-Secreted Enzymes in Patients With Polycystic Ovary Syndrome. J Periodontol. 2017;88(11):1145–52.
7. Deepti, Tewari S, Narula SC, Singhal SR, Sharma RK. Effect of Non-Surgical Periodontal Therapy Along With Myo-Inositol on High-Sensitivity C-Reactive Protein and Insulin Resistance in Women With Polycystic Ovary Syndrome and Chronic Periodontitis: A Randomized Controlled Trial. J Periodontol. 2017;88(10):999–1011.
8. Saglam E, Canakcı CF, Sebin SO, Saruhan N, Ingec M, Canakcı H, Sezer U. Evaluation of Oxidative Status in Patients With Chronic Periodontitis and Polycystic Ovary Syndrome: A Cross-Sectional Study. J Periodontol. 2017:1–16.
9. Akcalı A, Bostanci N, Özçaka Ö, Öztürk-Ceyhan B, Gümüş P, Tervahartiala T, Husu H, Buduneli N, Sorsa T, Belibasakis GN. Elevated matrix metalloproteinase-8 in saliva and serum in polycystic ovary syndrome and association with gingival inflammation. Innate Immun. 2015;21(6):619–25.
10. Rahiminejad ME, Moaddab A, Zaryoun H, Rabiee S, Moaddab A, Khodadoustan A. Comparison of prevalence of periodontal disease in women with polycystic ovary syndrome and healthy controls. Dent Res J. 2015;12(6):507–12.
11. Akcalı A, Bostanci N, Özçaka Ö, Öztürk-Ceyhan B, Gümüş P, Buduneli N, Belibasakis GN. Association between polycystic ovary syndrome, oral microbiota and systemic antibody responses. PLoS One. 2014;9(9):e108074.
12. Porwal S, Tewari S, Sharma RK, Singhal SR, Narula SC. Periodontal status and high-sensitivity C-reactive protein levels in polycystic ovary syndrome with and without medical treatment. J Periodontol. 2014;85(10):1380–9.
13. Özçaka Ö, Buduneli N, Ceyhan BO, Akcali A, Hannah V, Nile C, Lappin DF. Is interleukin-17 involved in the interaction between polycystic ovary syndrome and gingival inflammation? J Periodontol. 2013;84(12):1827–37.
14. Özçaka Ö, Ceyhan BÖ, Akcali A, Biçakci N, Lappin DF, Buduneli N. Is there an interaction between polycystic ovary syndrome and gingival inflammation? J Periodontol. 2012;83(12):1529–37.
15. Dursun E, Akalın FA, Güncü GN, Çınar N, Aksoy DY, Tözüm TF, Kılınc K, Yıldız BO. Periodontal disease in polycystic ovary syndrome. Fertil Steril. 2011;95(1):320–3.
16. Kellesarian SV, Malignaggi VR, Kellesarian TV, Al-Kheraif AA, Alwageet MM, Malmstrom H, Romanos GE, Javed F. Association between periodontal disease and polycystic ovary syndrome: a systematic review. Int J Impot Res. 2017;29(3):89–95.
17. Asnani KP, Hingorani D, Kheur S, Deshmukh V, Romanos GE. Expression of nuclear receptors of gingiva in polycystic ovarian syndrome: a preliminary case study. Aust Dent J. 2014;59(2):252–7.
18. Moore AM, Campbell RE. Polycystic ovary syndrome: Understanding the role of the brain. Front Neuroendocrinol. 2017;46:1–14.
19. Könönen E, Müller HP. Microbiology of aggressive periodontitis. Periodontol 2000. 2014;65(1):46–78.
20. Tsuchida S, Satoh M, Takiwaki M, Nomura F. Ubiquitination in Periodontal Disease: A Review. Int J Mol Sci. 2017;18(7):pii: E1476.
21. Han YW. Fusobacterium nucleatum: a commensal-turned pathogen. Curr Opin Microbiol. 2015;23:141–7.
22. Tanaka K, Miyake Y, Hanioka T, Arakawa M. Relationship between IL1 gene polymorphisms and periodontal disease in Japanese women. DNA Cell Biol. 2014;33(4):227–33.
23. Tsaousoglou P, Nietzsche S, Cachovan G, Sculean A, Eick S. Antibacterial activity of moxifloxacin on bacteria associated with periodontitis within a biofilm. J Med Microbiol. 2014;63(Pt 2):284–92.
24. Jiang ZL, Cui YQ, Gao R, Li Y, Fu ZC, Zhang B, Guan CC. Study of TNF-α, IL-1β and LPS levels in the gingival crevicular fluid of a rat model of diabetes mellitus and periodontitis. Dis Markers. 2013;34(5):295–304.
25. Yucel-Lindberg T, Båge T. Inflammatory mediators in the pathogenesis of periodontitis. Expert Rev Mol Med. 2013;15:e7.
26. Gao L, Gu Y, Yin X. High Serum Tumor Necrosis Factor-Alpha Levels in Women with Polycystic Ovary Syndrome: A Meta-Analysis. PLoS One. 2016;11(10):e0164021.
27. Urrútia G, Bonfill X. [PRISMA declaration: a proposal to improve the publication of systematic reviews and meta-analyses]. Med Clin. 2010;135(11):507–11.
28. Zeng X, Zhang Y, Kwong JS, Zhang C, Li S, Sun F, Niu Y, Du L. The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med. 2015;8(1):2–10.
29. Laganà AS, Rossetti P, Buscema M, La Vignera S, Condorelli RA, Gullo G, Granese R, Triolo O. Metabolism and Ovarian Function in PCOS Women: A Therapeutic Approach with Inositols. Int J Endocrinol. 2016;2016:6306410.
30. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81(1):19–25.
31. McCartney CR, Marshall JC. Clinical Practice. Polycystic Ovary Syndrome. N Engl J Med. 2016;375(1):54–64.
32. Diamanti-Kandarakis E, Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev. 2012;33(6):981–1030.
33. Stepto NK, Cassar S, Joham AE, Hutchison SK, Harrison CL, Goldstein RF, Teede HJ. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod. 2013;28(3):777–84.
34. Rosenfield RL, Ehrmann DA. The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. Endocr Rev. 2016;37(5):467–520.
35. Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome. Endocr Rev. 2015;36(5):487–525.
36. Kosova G, Urbanek M. Genetics of the polycystic ovary syndrome. Mol Cell Endocrinol. 2013;373(1-2):29–38.
37. Shi Y, Zhao H, Shi Y, Cao Y, Yang D, Li Z, Zhang B, Liang X, Li T, Chen J, Shen J, Zhao J, You L, Gao X, Zhu D, Zhao X, Yan Y, Qin Y, Li W, Yan J, Wang Q, Zhao J, Geng L, Ma J, Zhao Y, He G, Zhang A, Zou S, Yang A, Liu J, Li W, Li B, Wan C, Qin Y, Shi J, Yang J, Jiang H, Xu JE, Qi X, Sun Y, Zhang Y, Hao C, Ju X, Zhao D, Ren CE, Li X, Zhang W, Zhang Y, Zhang J, Wu D, Zhang C, He L, Chen ZJ. Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet. 2012;44(9):1020–5.
38. Du J, Wang J, Sun X, Xu X, Zhang F, Wang B, Shi Y, Chen ZJ. Family-based analysis of INSR polymorphisms in Chinese PCOS. Reprod Biomed Online. 2014;29(2):239–44.
39. Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JS, Ong KK, Perry JR. Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Nat Commun. 2015;6:8464.
40. Azziz R. PCOS in 2015: New insights into the genetics of polycystic ovary syndrome. Nat Rev Endocrinol. 2016;12(2):74–5.
41. Cui L, Li G, Zhong W, Bian Y, Su S, Sheng Y, Shi Y, Wei D, Zhang W, Zhao H, Chen ZJ. Polycystic ovary syndrome susceptibility single nucleotide polymorphisms in women with a single PCOS clinical feature. Hum Reprod. 2015;30(3):732–6.
42. Jones MR, Brower MA, Xu N, Cui J, Mengesha E, Chen YD, Taylor KD, Azziz R, Goodarzi MO. Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity. PLoS Genet. 2015;11(8):e1005455.
43. Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15.
44. Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, Pfeifer M, Pignatelli D, Pugeat M, Yildiz BO, ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–29.
45. Jalilian A, Kiani F, Sayehmiri F, Sayehmiri K, Khodaee Z, Akbari M. Prevalence of polycystic ovary syndrome and its associated complications in Iranian women: A meta-analysis. Iran J Reprod Med. 2015;13(10):591–604.
46. Dumesic DA, Lobo RA. Cancer risk and PCOS. Steroids. 2013;78(8):782–5.
47. Kubota T. Update in polycystic ovary syndrome: new criteria of diagnosis and treatment in Japan. Reprod Med Biol. 2013;12(3):71–7.
48. Bachanek M, Abdalla N, Cendrowski K, Sawicki W. Value of ultrasonography in the diagnosis of polycystic ovary syndrome - literature review. J Ultrason. 2015;15(63):410–22.
49. Thomas EL, Parkinson JR, Frost GS, Goldstone AP, Doré CJ, McCarthy JP, Collins AL, Fitzpatrick JA, Durighel G, Taylor-Robinson SD, Bell JD. The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat. Obesity. 2012;20(1):76–87.
50. Hung SP, Chen CY, Guo FR, Chang CI, Jan CF. Combine body mass index and body fat percentage measures to improve the accuracy of obesity screening in young adults. Obes Res Clin Pract. 2017;11(1):11–8.
2. Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO. Polycystic ovary syndrome. Rev Dis Primers. 2016;2:16057.
3. Delitala AP, Capobianco G, Delitala G, Cherchi PL, Dessole S. Polycystic ovary syndrome, adipose tissue and metabolic syndrome. Arch Gynecol Obstet. 2017;296(3):405–19.
4. Trikudanathan S. Polycystic ovarian syndrome. Med Clin North Am. 2015;99(1):221–35.
5. Rutkowska AZ, Diamanti-Kandarakis E. Polycystic ovary syndrome and environmental toxins. Fertil Steril. 2016;106(4):948–58.
6. Akcalı A, Bostanci N, Özçaka O, Gümüş P, Öztürk-Ceyhan B, Tervahartiala T, Husu H, Buduneli N, Sorsa T, Belibasakis GN. Gingival Inflammation and Salivary or Serum Granulocyte-Secreted Enzymes in Patients With Polycystic Ovary Syndrome. J Periodontol. 2017;88(11):1145–52.
7. Deepti, Tewari S, Narula SC, Singhal SR, Sharma RK. Effect of Non-Surgical Periodontal Therapy Along With Myo-Inositol on High-Sensitivity C-Reactive Protein and Insulin Resistance in Women With Polycystic Ovary Syndrome and Chronic Periodontitis: A Randomized Controlled Trial. J Periodontol. 2017;88(10):999–1011.
8. Saglam E, Canakcı CF, Sebin SO, Saruhan N, Ingec M, Canakcı H, Sezer U. Evaluation of Oxidative Status in Patients With Chronic Periodontitis and Polycystic Ovary Syndrome: A Cross-Sectional Study. J Periodontol. 2017:1–16.
9. Akcalı A, Bostanci N, Özçaka Ö, Öztürk-Ceyhan B, Gümüş P, Tervahartiala T, Husu H, Buduneli N, Sorsa T, Belibasakis GN. Elevated matrix metalloproteinase-8 in saliva and serum in polycystic ovary syndrome and association with gingival inflammation. Innate Immun. 2015;21(6):619–25.
10. Rahiminejad ME, Moaddab A, Zaryoun H, Rabiee S, Moaddab A, Khodadoustan A. Comparison of prevalence of periodontal disease in women with polycystic ovary syndrome and healthy controls. Dent Res J. 2015;12(6):507–12.
11. Akcalı A, Bostanci N, Özçaka Ö, Öztürk-Ceyhan B, Gümüş P, Buduneli N, Belibasakis GN. Association between polycystic ovary syndrome, oral microbiota and systemic antibody responses. PLoS One. 2014;9(9):e108074.
12. Porwal S, Tewari S, Sharma RK, Singhal SR, Narula SC. Periodontal status and high-sensitivity C-reactive protein levels in polycystic ovary syndrome with and without medical treatment. J Periodontol. 2014;85(10):1380–9.
13. Özçaka Ö, Buduneli N, Ceyhan BO, Akcali A, Hannah V, Nile C, Lappin DF. Is interleukin-17 involved in the interaction between polycystic ovary syndrome and gingival inflammation? J Periodontol. 2013;84(12):1827–37.
14. Özçaka Ö, Ceyhan BÖ, Akcali A, Biçakci N, Lappin DF, Buduneli N. Is there an interaction between polycystic ovary syndrome and gingival inflammation? J Periodontol. 2012;83(12):1529–37.
15. Dursun E, Akalın FA, Güncü GN, Çınar N, Aksoy DY, Tözüm TF, Kılınc K, Yıldız BO. Periodontal disease in polycystic ovary syndrome. Fertil Steril. 2011;95(1):320–3.
16. Kellesarian SV, Malignaggi VR, Kellesarian TV, Al-Kheraif AA, Alwageet MM, Malmstrom H, Romanos GE, Javed F. Association between periodontal disease and polycystic ovary syndrome: a systematic review. Int J Impot Res. 2017;29(3):89–95.
17. Asnani KP, Hingorani D, Kheur S, Deshmukh V, Romanos GE. Expression of nuclear receptors of gingiva in polycystic ovarian syndrome: a preliminary case study. Aust Dent J. 2014;59(2):252–7.
18. Moore AM, Campbell RE. Polycystic ovary syndrome: Understanding the role of the brain. Front Neuroendocrinol. 2017;46:1–14.
19. Könönen E, Müller HP. Microbiology of aggressive periodontitis. Periodontol 2000. 2014;65(1):46–78.
20. Tsuchida S, Satoh M, Takiwaki M, Nomura F. Ubiquitination in Periodontal Disease: A Review. Int J Mol Sci. 2017;18(7):pii: E1476.
21. Han YW. Fusobacterium nucleatum: a commensal-turned pathogen. Curr Opin Microbiol. 2015;23:141–7.
22. Tanaka K, Miyake Y, Hanioka T, Arakawa M. Relationship between IL1 gene polymorphisms and periodontal disease in Japanese women. DNA Cell Biol. 2014;33(4):227–33.
23. Tsaousoglou P, Nietzsche S, Cachovan G, Sculean A, Eick S. Antibacterial activity of moxifloxacin on bacteria associated with periodontitis within a biofilm. J Med Microbiol. 2014;63(Pt 2):284–92.
24. Jiang ZL, Cui YQ, Gao R, Li Y, Fu ZC, Zhang B, Guan CC. Study of TNF-α, IL-1β and LPS levels in the gingival crevicular fluid of a rat model of diabetes mellitus and periodontitis. Dis Markers. 2013;34(5):295–304.
25. Yucel-Lindberg T, Båge T. Inflammatory mediators in the pathogenesis of periodontitis. Expert Rev Mol Med. 2013;15:e7.
26. Gao L, Gu Y, Yin X. High Serum Tumor Necrosis Factor-Alpha Levels in Women with Polycystic Ovary Syndrome: A Meta-Analysis. PLoS One. 2016;11(10):e0164021.
27. Urrútia G, Bonfill X. [PRISMA declaration: a proposal to improve the publication of systematic reviews and meta-analyses]. Med Clin. 2010;135(11):507–11.
28. Zeng X, Zhang Y, Kwong JS, Zhang C, Li S, Sun F, Niu Y, Du L. The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med. 2015;8(1):2–10.
29. Laganà AS, Rossetti P, Buscema M, La Vignera S, Condorelli RA, Gullo G, Granese R, Triolo O. Metabolism and Ovarian Function in PCOS Women: A Therapeutic Approach with Inositols. Int J Endocrinol. 2016;2016:6306410.
30. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81(1):19–25.
31. McCartney CR, Marshall JC. Clinical Practice. Polycystic Ovary Syndrome. N Engl J Med. 2016;375(1):54–64.
32. Diamanti-Kandarakis E, Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev. 2012;33(6):981–1030.
33. Stepto NK, Cassar S, Joham AE, Hutchison SK, Harrison CL, Goldstein RF, Teede HJ. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod. 2013;28(3):777–84.
34. Rosenfield RL, Ehrmann DA. The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. Endocr Rev. 2016;37(5):467–520.
35. Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome. Endocr Rev. 2015;36(5):487–525.
36. Kosova G, Urbanek M. Genetics of the polycystic ovary syndrome. Mol Cell Endocrinol. 2013;373(1-2):29–38.
37. Shi Y, Zhao H, Shi Y, Cao Y, Yang D, Li Z, Zhang B, Liang X, Li T, Chen J, Shen J, Zhao J, You L, Gao X, Zhu D, Zhao X, Yan Y, Qin Y, Li W, Yan J, Wang Q, Zhao J, Geng L, Ma J, Zhao Y, He G, Zhang A, Zou S, Yang A, Liu J, Li W, Li B, Wan C, Qin Y, Shi J, Yang J, Jiang H, Xu JE, Qi X, Sun Y, Zhang Y, Hao C, Ju X, Zhao D, Ren CE, Li X, Zhang W, Zhang Y, Zhang J, Wu D, Zhang C, He L, Chen ZJ. Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet. 2012;44(9):1020–5.
38. Du J, Wang J, Sun X, Xu X, Zhang F, Wang B, Shi Y, Chen ZJ. Family-based analysis of INSR polymorphisms in Chinese PCOS. Reprod Biomed Online. 2014;29(2):239–44.
39. Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JS, Ong KK, Perry JR. Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Nat Commun. 2015;6:8464.
40. Azziz R. PCOS in 2015: New insights into the genetics of polycystic ovary syndrome. Nat Rev Endocrinol. 2016;12(2):74–5.
41. Cui L, Li G, Zhong W, Bian Y, Su S, Sheng Y, Shi Y, Wei D, Zhang W, Zhao H, Chen ZJ. Polycystic ovary syndrome susceptibility single nucleotide polymorphisms in women with a single PCOS clinical feature. Hum Reprod. 2015;30(3):732–6.
42. Jones MR, Brower MA, Xu N, Cui J, Mengesha E, Chen YD, Taylor KD, Azziz R, Goodarzi MO. Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity. PLoS Genet. 2015;11(8):e1005455.
43. Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15.
44. Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, Pfeifer M, Pignatelli D, Pugeat M, Yildiz BO, ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–29.
45. Jalilian A, Kiani F, Sayehmiri F, Sayehmiri K, Khodaee Z, Akbari M. Prevalence of polycystic ovary syndrome and its associated complications in Iranian women: A meta-analysis. Iran J Reprod Med. 2015;13(10):591–604.
46. Dumesic DA, Lobo RA. Cancer risk and PCOS. Steroids. 2013;78(8):782–5.
47. Kubota T. Update in polycystic ovary syndrome: new criteria of diagnosis and treatment in Japan. Reprod Med Biol. 2013;12(3):71–7.
48. Bachanek M, Abdalla N, Cendrowski K, Sawicki W. Value of ultrasonography in the diagnosis of polycystic ovary syndrome - literature review. J Ultrason. 2015;15(63):410–22.
49. Thomas EL, Parkinson JR, Frost GS, Goldstone AP, Doré CJ, McCarthy JP, Collins AL, Fitzpatrick JA, Durighel G, Taylor-Robinson SD, Bell JD. The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat. Obesity. 2012;20(1):76–87.
50. Hung SP, Chen CY, Guo FR, Chang CI, Jan CF. Combine body mass index and body fat percentage measures to improve the accuracy of obesity screening in young adults. Obes Res Clin Pract. 2017;11(1):11–8.
Published
2018-02-27
How to Cite
ARBILDO, Heber et al.
Association between periodontal disease and polycystic ovary syndrome: A scoping review..
Journal of Oral Research, [S.l.], v. 7, n. 2, p. 70-78, feb. 2018.
ISSN 0719-2479.
Available at: <https://www.joralres.com/index.php/JOralRes/article/view/joralres.2018.018>. Date accessed: 18 apr. 2024.
doi: https://doi.org/10.17126/joralres.2018.018.
Issue
Section
Reviews
Keywords
polycystic ovary syndrome; periodontal disease; gingivitis; periodontitis; revision.
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