Pablo Betancourt Endodontic Laboratory, Center for Research in Dental Sciences (CICO), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile. | Department of Integral Adult Dentistry, Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile. http://orcid.org/0000-0002-9903-2920
Eulàlia Sans-Serramitjana Endodontic Laboratory, Center for Research in Dental Sciences (CICO), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile. | Department of Integral Adult Dentistry, Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile. | Center of Excellence in Translational Medicine-Scientific and Technology Bioresources Nucleus (CEMT-BIOREN), Universidad de La Frontera, Temuco, Chile. | Millennium Nucleus Bioproducts, Genomics and Environmental Microbiology (BioGEM), Avenida España 1680, 2390123 Valparaíso, Chile. http://orcid.org/0000-0001-5642-6965
Recent advances in metallurgy and heat-treated NiTi instruments have dramatically increased efficiency in root canal preparation, allowing clinicians to complete mechanical shaping in significantly less time and with fewer files.1,2 This technological progress has undeniable benefits, but it also raises a critical question: Does the acceleration of instrumentation compromise the biological foundation of endodontic therapy?
The complexity of root canal morphology remains a major challenge. Micro-CT investigations have demonstrated that 10–80% of canal surfaces—particularly in oval and flattened canals—remain uninstrumented, irrespective of the instrumentation system utilized.3 These anatomical complexities mean that irrigation, not instrumentation, is the decisive factor for effective disinfection. Sodium hypochlorite (NaOCl), the most widely used irrigant, requires sufficient contact time to disrupt biofilms and dissolve organic tissue, yet accelerated treatments risk reducing this crucial step.
The trend toward minimally invasive endodontics (MIE) further accentuates this paradox. Conservative shaping preserves dentin and improves structural integrity, but also narrows preparation and limits mechanical debridement, thereby increasing reliance on irrigation protocols.4 In this context, adjunctive technology such as laser activation holds promise. It can enhance irrigant penetration and exchange, potentially compensating for reduced canal enlargement and treatment time.5 However, clinical evidence remains limited, and robust trials are needed to confirm its effectiveness in improving periapical healing outcomes.
In our view, the central challenge for contemporary endodontics is to reconcile speed, biology, and conservation. Technological efficiency must not undermine the biological requirement for thorough disinfection. Irrigation time, enhanced by but not replaced with activation methods, remains essential to achieve predictable long-term success.
1. Martins JNR, Silva EJNL, Marques D, Pereira MR, Vieira VTL, Arantes-Oliveira S, Martins RF, Braz Fernandes F, Versiani M. Design, Metallurgical Features, and Mechanical Behaviour of NiTi Endodontic Instruments from Five Different Heat-Treated Rotary Systems. Materials (Basel). 2022;15(3):1009. https://doi.org/10.3390/ma15031009. PMID: 35160955; PMCID: PMC8840527.
2. Kang YJ, Kwak SW, Ha JH, Gambarini G, Kim HC. Fracture resistances of heat-treated nickel-titanium files used for minimally invasive instrumentation. BMC Oral Health. 2025;25(1):126. https://doi.org/10.1186/s12903-025-05487-4. PMID: 39849 421; PMCID: PMC11761776.
3. Siqueira Junior JF, Rôças IDN, Marceliano-Alves MF, Pérez AR, Ricucci D. Unprepared root canal surface areas: causes, clinical implications, and therapeutic strategies. Braz Oral Res. 2018;32(suppl 1):e65. https://doi.org/10.1590/1807-3107bor-2018.vol32.0065. PMID: 30365606.
4. Kwon SK, Seog M, Kim D, Jung IY. Impact of minimally invasive root canal treatment on healing outcomes in a randomized clinical trial. Sci Rep. 2025;15(1):23260. https://doi.org/10.1038/s41598-025-02905-z. PMID: 40603366; PMCID: PMC12222528.
5. Betancourt P, Merlos A, Sierra JM, Arnabat-Dominguez J, Viñas M. Er,Cr:YSGG Laser-Activated Irrigation and Passive Ultrasonic Irrigation: Comparison of Two Strategies for Root Canal Disinfection. Photobiomodul Photomed Laser Surg. 2020;38(2):91-97. https://doi.org/10.1089/photob.2019.4645. Epub 2019 Aug 9. PMID: 31397611.
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Pablo Betancourt (P.B.) acknowledges the DIUFRO project PAB24-0021. Eulàlia Sans-Serramitjana (E.S.-S) from the Chilean Government’s National Agency for Research and Development (ANID) project (SIA Project No. 85240304).
Pablo Betancourt (P.B.) reconoce el proyecto DIUFRO PAB24-0021. Eulàlia Sans-Serramitjana (E.S.-S) del proyecto de la Agencia Nacional de Investigación y Desarrollo (ANID) del Gobierno de Chile (Proyecto SIA N° 85240304).
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