TY - JOUR AU - Aragon-Martinez, Othoniel AU - Loredo-Escobar, Karen AU - Cepeda-Bravo, Juan AU - Martinez-Morales, Flavio AU - Gonzalez-Rivera, Maria AU - Aranda Romo, Saray PY - 2022 TI - Correlation between salivary biomarkers and plaque-induced gingivitis exacerbated by pregnancy JF - Journal of Oral Research; Vol 11 No 3 (2022): May-June DO - 10.17126/joralres.2022.032 KW - N2 - Objetive: To evaluate the correlation between salivary biomarkers (the salivary antioxidant ability, salivary level of polyphenols, and other antioxidants) with plaque-induced gingivitis exacerbated by pregnancy in pregnant and nonpregnant women. Material and Methods: For this observational study, medical records, dental examinations, and analyses of saliva samples were carried out in pregnant and nonpregnant women. A p-value of <0.05 was considered significant. Results: The pregnant women (n =17) exhibited a lower antioxidant capacity (p-value=0.0041), higher levels of polyphenols, gingival index, bleeding on probing, and subjects consuming mineral-enriched products (p-value from <0.0001 to 0.0466), and unchanged levels of phosphotungstic acid reactive substances, proteins, oral hygienic habits, plaque index and probing depth (p-value from 0.0683 to 0.8358), in comparison with the nonpregnant women (n=9). Also, a positive correlation between the gingival index and salivary polyphenol content was observed (r-value = 0.4087, p-value = 0.0202). Conclusion: The salivary polyphenols correlate with plaque-induced gingivitis exacerbated by pregnancy, suggesting a deficiency of salivary antioxidant protection. UR - https://www.joralres.com/index.php/JOralRes/article/view/joralres.2022.032