Bone healing of dental alveoli in smokers with platelet-rich plasma obtained using single or double centrifugation.

Jonathan Harris Ricardo, María Osorio Daguer, Natalia Fortich Mesa

Abstract


Introduction: the habit of smoking alters the bone healing process,a problem to consider in oral surgery. Objective: To evaluate the bone healing ofdental alveoli with PRP obtained using single or double centrifugation in smokers.Methodology: Extraction of mandibular third molars was performed in a studypopulation divided into smoking group (A), which had PRP applied with theprotocol using a single centrifugation step (P1C) in the alveolus of tooth 38 and theprotocol of double centrifugation (P2C) in alveolus of tooth 48; a smoking group(B), to whom no PRP was applied; and a non-smokers group (C) to whom PRPwas applied obtained using P1C and P2C protocol. Radiographic examinationwas performed at 8, 30 and 60 days post procedure. Results: Thirty patients metthe criteria, 57% were female. When evaluating bone healing between the groupof smokers and non-smokers, statistically significant differences were observed inthe non-smoking group at 30 and 60 days, showing better results with the P2Cprotocol (p<0.005). Statistically significant differences were found at 30 and 60days (p<0.005), both with the P1C and P2C when comparing bone healing ofgroup A and B. Conclusions: Bone healing in the alveoli of mandibular thirdmolars that which PRP applied was higher in non-smoking patients, comparedwith the group of smokers. Bone healing was better in patients smokers to whomPRP was applied than those without PRP treatment. Regarding the method ofobtaining PRP, bone healing was better when a double centrifugation protocol(P2C) was applied.

Keywords


bone regeneration; dental alveolus; platelet-rich plasma; smoking.

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