Analysis of prevalence and diagnostic criteria of molar-incisor hipomineralization.

  • Lunna Farias School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil.
  • Isla Camilla Carvalho Laureano School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil.
  • Catarina Ribeiro Barros de Alencar School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil.
  • Alessandro Leite Cavalcanti Department of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil.

Abstract

To identify the prevalence and diagnostic criteria of Molar-Incisor Hipomineralization (MIH) in the scientific literature. Materials and Methods: This is a bibliographical research conducted through the analysis of indexed articles until October 2017 in the PubMed, Web of Science and Scopus databases. The Medical Subject Headings (MESH) used were "Dental Enamel Hypoplasia" and "Molar Incisor Hypomineralization". The analysis of articles was carried out by two reviewers, who collected information independently. The following information was collected: author, year of publication, place of work (continent and country), sample calculation, sample number, age of participants, type of study, prevalence of molar-incisor hypomineralization and criteria used for diagnosis. Data were tabulated using Microsoft Excel for Windows and presented using descriptive statistics. Results: A total of 484 articles were found and 57 were included in the study. Most of the studies were conducted in Europe (35%), and 31.6% of the studies mentioned using a probability sampling. The number of study participants ranged from 99 for a study in Brazil to 3,591 in Kenya. The most frequent age was 8 years, while the predominant type of study was cross-sectional (91.2%). The prevalence varied from 0.4% to 37.3% and most studies (73.6%) employed the European Academy of Pediatric Dentistry criteria for the diagnosis of MIH. Conclusion: There is great variability in prevalence in different countries, probably due to the use of different diagnostic criteria being used, and due to different age groups and geographical variation.

References

1. Weerheijm KL, Duggal M, Mejàre I, Papagiannoulis L, Koch G, Martens LC, Hallonsten AL. Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the european meeting on MIH held in Athens. Eur J Paediatr Dent. 2003; 4(3):110-13.
2. Andrade NS, Pontes AS, de Sousa Paz HE, de Moura MS, Moura LF, Lima MD. Molar incisor hypomineralization in HIV-infected children and adolescents. Spec Care Dentist. 2017; 37(1):28-37.
3. Teixeira RJPB, Andrade NS, Queiroz LCC, Mendes FM3, Moura MS, Moura LFAD, Lima MDM. Exploring the association between genetic and environmental factors and molar incisor hypomineralization: evidence from a twin study. Int J Paediatr Dent. 2018; 28(2):198-206.
4. Zhao D, Dong B, Yu D, Ren Q, Sun Y. The prevalence of molar incisor hypomineralization: evidence from 70 studies. Int J Paediatr Dent. 2017; 28(2):170-9.
5. Rodrigues FCN, Ribeiro PHB, Thomaz EBAF, Lima GQT, Neves PAM, Ribeiro CCC. Molar-incisor hypomineralization in schoolchildren of Sao Luis, Brazil, Maranhao: Prevalence and associated factors. Braz Res Pediatr Dent Integrat Clin 2015; 15(1):271-8.
6. Jasulaityte L, Veerkamp JS, Weerheijm KL. Molar incisor hypomineralization: review and prevalence data from study of primary school children in Kaunas (Lithuania). Eur Arch Paed Dent. 2007; 8(2):87-94.
7. Elfrink MEC, ten Cate JM, Jaddoe VW, Hofman A, Moll HA, Veerkamp JS. Deciduous molar hypomineralization and molar incisor hypomineralization. J Dent Res. 2012; 91(6):551-5.
8. Yannam, SD, Amarlal D, Rekha CV. Prevalence of molar incisor hypomineralization in school children aged 8-12 years in Chennai. J Indian Soc Pedod Prev Dent. 2016; 34(2):134-8.
9. Da Costa-Silva CM, Jeremias F, de Souza JF, Cordeiro RCL, Santos-Pinto L, Zuanon ACC. Molar incisor hypomineralization: prevalence, severity and clinical consequences in Brazilian children. Int J Paediatr Dent. 2010; 20(6):426-34.
10. Jeremias F, de Souza JF, Silva CMC, Cordeiro RdeCL, Zuanon ACC, Santos-Pinto L. Dental caries experience and molar-incisor hypomineralization. Acta Odontol Scand. 2013; 71(3-4):870-6.
11. Koch G, Hallonsten AL, Ludvigsson N, Hansson BO, Holst A, Ullbro C. Epidemiologic study of idiopathic enamel hypomineralization in permanent teeth of Swedish children. Community Dent Oral Epidemiol. 1987; 15(5):279-85.
12. Lygidakis NA, Wong F, Jalevik B, Vierrou AM, Alaluusua S, Espelid I. Best Clinical Practice Guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH): An EAPD Policy Document. Eur Arch Paediatr Dent. 2010; 11(2):75-81.
13. Ahmadi R, Ramazani N, Nourinasab R. Molar incisor hypomineralization: a study of prevalence and etiology in a group of Iranian children. Iran J Pediatr. 2012; 22(2):245-51.
14. Buchgraber B, Kqiku L, Ebeleseder KA. Molar incisor hypomineralization: proportion and severity in primary public school children in Graz, Austria. Clin Oral Investig. 2017; 22(2):757-62.
15. Salem K, Aziz D, Asadi M. Prevalence and predictors of molar incisor hypomineralization (MIH) among rural children in northern Iran. Iranian J Public Health. 2016; 45(11):1528-30.
16. Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation, aetiology and management. Dent Update. 2004; 31(1):9-12.
17. Pereira L, Miasato JM. Mantenedor de espaço estético-funcional em odontopediatria. Rev Odontol Univ Cid São Paulo. 2010; 22(2):154-62.
18. Dantas-Neta NB, Moura LF, Cruz PF, Moura MS, Paiva SM, Martins CC, Lima MD. Impact of molar-incisor hypomineralization on oral health-related quality of life in schoolchildren. Braz Oral Res. 2016; 30(1):117.
19. Hernandez M, Boj JR, Espasa E. Do we really know the prevalence of MIH? J Clin Pediatr Dent. 2016; 40(4):259-63.
20. Kemoli AM. Prevalence of molar incisor hypomineralisation in six to eight year-olds in two rural divisions in Kenya. East Afr Med J. 2008; 85(10):514-9.
21. Wogelius P, Haubek D, Poulsen S. Prevalence and distribution of demarcated opacities in permanent 1st molars and incisors in 6- to 8-year-old Danish children. Acta Odont Scand. 2008; 66(1):58-64.
22. Kühnisch J, Heitmüller D, Thiering E, Brockow I, Hoffmann U, Neumann C, Heinrich-Weltzien R, Bauer CP, von Berg A, Koletzko S, Garcia-Godoy F, Hickel R, Heinrich J.Proportion and extent of manifestation of molar-incisor-hypomineralizations according to different phenotypes. J Public Health Dent. 2012; 74(1):42-9.
23. Garcia-Margarit M, Catalá-Pizarro M, Montiel-Company JM, Almerich-Silla JM. Epidemiologic study of molar-incisor hypomineralization in 8-year-old Spanish children. Int J Paediatr Dent. 2014; 24(1):14-22.
24. Kevrekidou A, Kosma I, Arapostathis K, Kotsanos N. Molar incisor hypomineralization of eight and 14-year-old children: prevalence, severity, and defect characteristics. Pediatr Dent. 2015; 37(5):455-61.
25. Kühnisch J, Thiering E, Kratzsch J, Heinrich-Weltzien R, Hickel R, Heinrich J; GINIplus study group; LISAplus study group. Elevated serum 25(OH)-vitamin D levels are negatively correlated with molar-incisor hypomineralization. J Dent Res. 2015; 94(2):381-7.
26. Negre-barber A, Montiel-Company JM, Boronat-Catalá M, Catalá-Pizarro M, Almerich-Silla JM. Hypomineralized second primary molars as predictor of molar incisor hypomineralization. Sci Rep. 2016; 6:1-6.
27. Bhaskar SA, Hegde S. Molar-incisor hypomineralization: prevalence, severity and clinical characteristics in 8 to 13-year-old children of Udaipur, India. J Indian Soc Pedod Prev Dent. 2014; 32(4):322-9.
28. Subramaniam P, Gupta T, Sharma A. Prevalence of molar incisor hypomineralization in 7–9-year-old children of Bengaluru city, India. Contemp Clin Dent. 2016; 7(1):11-15.
29. de Lima Mde D, Andrade MJ, Dantas-Neta NB, Andrade NS, Teixeira RJ, de Moura MS, de Deus Moura Lde F5.Epidemiologic study of molar-incisor hypomineralization in schoolchildren in North-Eastern Brazil. Pediatr Dent. 2015; 37(7):513-9
30. Tourino LFPG, Corrêa-Faria P, Ferreira RC, Bendo CB, Zarza PM, Vale MP. Association between molar incisor hypomineralization in schoolchildren and both prenatal and postnatal factors: a population-based study. PLoS One. 2016; 11(6):e0156332.
31. Temilola OD, Folayan MO, Oyedele T. The prevalence and pattern of deciduous molar hypomineralization and molar-incisor hypomineralization in children from a suburban population in Nigeria. BMC Oral Health. 2015; 15(73):1-6.
32. Temilola OD, Folayan MO. Distinguishing predisposing factors for enamel hypoplasia and molar-incisor hypomine-ralization in children in Ile-Ife, Nigeria. Braz J Oral Sci. 2015; 14(4):318-22.
33. Oyedele TA, Folayan MO, Oziegbe EO. Hypomineralised second primary molars: prevalence, pattern and associated comorbidities in 8- to 10-year-old children in Ile-Ife, Nigeria. BMC Oral Health. 2016; 16(65):1-7.
34. Condò R, Perugia C, Maturo P, Docimo R. MIH: Epidemiologic clinic study in paediatric patient. Oral Implantol. 2012; 5(2-3):58-69
35. Preusser SE, Ferring V, Wleklinski C, Wetzel WE. Prevalence and severity of molar incisor hypomineralization in a region of Germany - a brief communication. J Public Health Dent. 2007; 67(3):148-50.
36. Jälevik B, Klingberg G, Barregard L, Noren JG. The prevalence of demarcated opacities in permanent first molars in a group of Swedish children. Acta Odontol Scand. 2001; 59(5):255-60.
37. Laisi S, Ess A, Sahlberg C, Arvio P, Lukinmaa PL, Alaluusua S. Amoxicillin may cause molar incisor hypomineralization. J Dent Res. 2009; 88(2):132-6.
38. Janković S, Ivanović M, Davidović B, Lecić J. Distribution and characteristics of molar-incisor hypomineralization. Vojnosanit Pregl. 2014; 71(8):730-4.
39. Wuollet E, Laisi S, Salmela E, Ess A, Alaluusua S. Background factors of molar-incisor hypomineralization in a group of Finnish children. Acta Odontol Scand. 2014; 72(8):963-9.
40. Opydo-Szymaczek J, Gerreth K. Developmental enamel defects of the permanent first molars and incisors and their association with dental caries in the region of Wielkopolska, Western Poland. Oral Health Prev Dent. 2015; 13(5):461-9.
41. Schmalfuss A, Stenhagen KR, Tveit AB, Crossner CG, Espelid I. Canines are affected in 16-year-olds with molar-incisor hypomineralisation (MIH): an epidemiological study based on the Tromsø study: "Fit Futures". Eur Arch Paediatr Dent. 2016; 17(2):107-13.
42. Van der Tas JT, Elfrink MEC, Vucic S, Heppe DHM, Verkamp JSJ, Jaddoe VWV, et al. Association between bone mass and dental hypomineralization. J Dent Res. 2016; 95(4):395-401.
43. Wuollet E, Laisi S, Salmela E, Ess A, Alaluusua S. Molar-incisor hypomineralization and the association with childhood illnesses and antibiotics in a group of Finnish children. Acta Odontol Scand. 2016; 74(5):416-22.
44. Pitiphat W, Luangchaichaweng S, Pungchanchaikul P, Angwaravong O, Chansamak N. Factors associated with molar incisor hypomineralization in Thai children. Eur J Oral Sci. 2014; 122(4):265-70.
45. Cho SY, Ki Y, Chu V. Molar incisor hypomineralization in Hong Kong Chinese children. Int J Paediatr Dent. 2008; 18(5):348-52.
46. Kuscu OO, Caglar E, Aslan S, Durmusoglu E, Karademir A, Sandalli N. The prevalence of molar incisor hypomineralization (MIH) in a group of children in a highly polluted urban region and a windfarm-green Energy Island. Int J Paediatr Dent. 2009; 19(3):176-85.
47. Allazam SM, Alaki SM, El Meligy OAS. Molar incisor hypomineralization, prevalence and etiology. Int J Dent. 2014; 2014(234508):1-8.
48. Pitiphat W, Savisit R, Chansamak N, Subarnbhesaj A. Molar incisor hypomineralization and dental caries in six- to seven-year-old Thai children. Pediatr Dent. 2014; 36(7):478-82
49. Shrestha R, Upadhaya S, Bajracharya M. Prevalence of molar incisor hypomineralisation among school children in Kavre. Kathmandu Univ Med J. 2014; 12(45):38-42.
50. Hussein AS, Faisal M, Haron M, Ghanim AM, Abu-Hassan MI. Distribution of molar incisor hypomineralization in Malaysian children attending university dental clinic. J Clin Pediatr Dent. 2015; 39(3):219-23.
51. Kirthiga M, Poornima P, Praveen R, Gayathri P, Manju M, Priya M. Prevalence and severity of molar incisor hypomineralization in children aged 11-16 years of a city in Karnataka, Davangere. J Indian Soc Pedod Prev Dent. 2015; 33(3):213-7.
52. Ng JJ, Eu OC, Nair R, Hong CH. Prevalence of molar incisor hypomineralization (MIH) in Singaporean children. Int J Paediatr Dent. 2015; 25(2):73-8.
53. Mishra A, Pandey RK. Molar Incisor Hypomineralization: an epidemiological study with prevalence and etiological factors in Indian pediatric population. Int J Clin Pediatr Dent. 2016; 9(2):167-71.
54. Mittal N. Phenotypes of enamel hypomineralization and molar incisor hypomineralization in permanent dentition: identification, quantification and proposal for classification. J Clin Pediatr Dent. 2016; 40(5):367-74.
55. Mittal R, Chandak S, Chandwani M, Singh P, Pimpale J. Assessment of association between molar incisor hypomine-ralization and hypomineralized second primary molar. J Int Soc Prev Community Dent. 2016; 6(1):34-9.
56. Silva Júnior IF, Aguiar NL, Barros WRC, da Silva LS, Arantes DC, do Nascimento LS. Prevalence and severity of molar incisor hypomineralization in students of Belém, Brazil. Braz Res Pediatr Dent Integr Clin. 2015; 15(1):377-85.
57. Jeremias F, Pierri RA, Souza JF, Fragelli CM, Restrepo M, Finoti LS, Bussaneli DG, Cordeiro RC, Secolin R, Maurer-Morelli CV, Scarel-Caminaga RM, Santos-Pinto L. Family-based genetic association for molar-incisor hypomineralization. Caries Res. 2016; 50(3):310-18.
58. Biondi AM, Cortese SG, Martínez K, Ortolani AM, Sebelli PM, Ienco M, Paván VH, Mendel N, Bertolino M, Hecht P. Prevalence of molar incisor hypomineralization in the city of Buenos Aires. Acta Odontol Latinoam. 2011; 24(1):81-5.
59. Biondi AM, López Jordi Mdel C, Cortese SG, Alvarez L, Salveraglio I, Ortolani AM. Prevalence of molar-incisor hypomineralization (MIH) in children seeking dental care at the Schools of Dentistry of the University of Buenos Aires (Argentina) and University of la Republica (Uruguay). Acta Odontol Latinoam. 2012; 25(2):224-30
60. Jordi Mdel C, Cortese SG, Álvarez L, Salveraglio I, Ortolani AM, Biondi AM. [Comparison of the prevalence of molar incisor hypomineralization among children with different health care coverage in the cities of Buenos Aires (Argentina) and Montevideo (Uruguay)]. Salud Colect. 2014; 10(2):243-51.
61. Hanan SA, Filho Ade OA, Medina PO, Cordeiro RDdeCL, Santos-Pinto L, Zuanon ÂCC. Molar-Incisor hypomi-neralization in schoolchildren of Manaus, Brazil. Braz Res Pediatr Dent Integr Clin. 2015; 15(1):309-17.
62. Gurrusquieta BJ, Núñez VM, López ML. Prevalence of Molar Incisor Hypomineralization in Mexican children. J Clin Pediatr Dent. 2017; 41(1):18-21.
63. Fteita D, Ali A, Alaluusua S. Molar-incisor hypomi-neralization (MIH) in a group of school aged children in Benghazi, Libya. Eur Arch Paediatr Dent. 2006; 7(2):92-5.
64. Oyedele TA, Folayan MO, Sofowora CA, Oziegbe E. Co-morbidities associated with molar-incisor hypomineralisation in 8 to 16 year old pupils in Ile-Ife, Nigeria. BMC Oral Health. 2015;15:37.
65. lencar CRB, Cavalcanti AL. Molar incisor hypomine-ralization - A challenge of pediatric dentistry? J Oral Res 2018; 7(3):84-5.
Published
2019-07-24
How to Cite
FARIAS, Lunna et al. Analysis of prevalence and diagnostic criteria of molar-incisor hipomineralization.. Journal of Oral Research, [S.l.], v. 8, n. 3, p. 254-262, july 2019. ISSN 0719-2479. Available at: <http://www.joralres.com/index.php/JOR/article/view/819>. Date accessed: 20 sep. 2019. doi: https://doi.org/10.17126/jor.v0i0.819.
Section
Reviews